Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYN3 All Species: 16.97
Human Site: S473 Identified Species: 41.48
UniProt: O14994 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14994 NP_003481.3 580 63303 S473 Q Q P L S P Q S G S P Q Q Q R
Chimpanzee Pan troglodytes XP_515096 579 63181 S472 Q Q P L S P Q S G S P Q Q Q R
Rhesus Macaque Macaca mulatta XP_001086745 582 63133 R475 P G K V L P P R R L P P G P S
Dog Lupus familis XP_850873 579 63100 P472 G Q Q P L S P P S G S P Q Q R
Cat Felis silvestris
Mouse Mus musculus Q8JZP2 579 63326 S472 Q Q P V S P Q S G S P Q Q Q R
Rat Rattus norvegicus O70441 579 63330 S472 Q Q P V S P Q S G S P Q Q Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510451 589 64300 S482 Q Q P Q S P Q S S S P Q R S P
Chicken Gallus gallus
Frog Xenopus laevis NP_001079204 580 63774 R473 L P K A N S L R F T A W L P T
Zebra Danio Brachydanio rerio NP_001119909 670 72335 Q562 P T Q G G P Q Q T Q D A P Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24546 1025 107509 D698 Q E R V N P F D K E P S K S G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 60.6 93.9 N.A. 92.4 92 N.A. 74.8 N.A. 68 52.8 N.A. 27.1 N.A. N.A. N.A.
Protein Similarity: 100 99.6 74.2 95.5 N.A. 95.1 95.3 N.A. 82.8 N.A. 79.1 65.9 N.A. 37.7 N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 26.6 N.A. 93.3 93.3 N.A. 66.6 N.A. 0 20 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 26.6 N.A. 100 100 N.A. 73.3 N.A. 13.3 20 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % F
% Gly: 10 10 0 10 10 0 0 0 40 10 0 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 20 0 0 0 0 0 10 0 0 0 10 0 0 % K
% Leu: 10 0 0 20 20 0 10 0 0 10 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 10 50 10 0 80 20 10 0 0 70 20 10 20 20 % P
% Gln: 60 60 20 10 0 0 60 10 0 10 0 50 50 60 0 % Q
% Arg: 0 0 10 0 0 0 0 20 10 0 0 0 10 0 50 % R
% Ser: 0 0 0 0 50 20 0 50 20 50 10 10 0 20 10 % S
% Thr: 0 10 0 0 0 0 0 0 10 10 0 0 0 0 10 % T
% Val: 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _